Journal of Negative Results in BioMedicine

September 3, 2010 – 9:58 am

A collegue of mine pointed out that there is a journal for negative results in biomedical research,the Journal of Negative Results in BioMedicine:

Journal of Negative Results in BioMedicine is ready to receive manuscripts on all aspects of unexpected, controversial, provocative and/or negative results/conclusions in the context of current tenets, providing scientists and physicians with responsible and balanced information to support informed experimental and clinical decisions.

Not every unexpected observation, controversial conclusion or proposed model will turn out to be of such groundbreaking significance. Nor will they even be confirmed by subsequent scientific progress. However, we strongly believe that such “negative” observations and conclusions, based on rigorous experimentation and thorough documentation, ought to be published in order to be discussed, confirmed or refuted by others. In addition, publishing well documented failures may reveal fundamental flaws and obstacles in commonly used methods, drugs or reagents such as antibodies or cell lines, ultimately leading to improvements in experimental designs and clinical decisions.

Certainly, there was a niche for that and I’m curious to see how it evolves.


Study Suggests Hormone Therapy Offers Potential Protective Effect again Colon Cancer in Older Women

September 3, 2010 – 7:00 am

In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal cancer risk. However, the mechanisms for the apparent protective association are still unclear. The study, being presented at the annual meeting of the American Association for Cancer Research, was designed to look at possible links between estrogen exposure and colon cancer molecular subtypes, to determine how these hormones might function as anti-cancer agents. David Limsui, M.D., a fellow in the Department of Gastroenterology at Mayo Clinic, is the study’s lead author.


HHS issues $153M contract for antineutropenia drug

September 3, 2010 – 7:00 am The U.S. Department of Health and Human Services (HHS) Biomedical Advanced (more)

Women of Mexican origin at higher risk for breast cancer

September 3, 2010 – 7:00 am Women of Mexican origin in the U.S. are younger when diagnosed with breast (more)

Staggering rad work shifts improves patient care

September 3, 2010 – 7:00 am Putting staggered radiologist work shifts in place can improve communications (more)

Recruiting firm predicts rad shortage

September 3, 2010 – 7:00 am Physician recruitment firm LocumTenens.com is predicting a possible shortage (more)

Cancer cost world economy $895B in 2008

September 3, 2010 – 7:00 am Cancer has the most devastating economic effects of any cause of death in the (more)

SPECT/CT for thyroid cancer helps avoid more imaging tests

September 3, 2010 – 7:00 am Use of SPECT/CT can help avoid additional imaging tests for thyroid cancer (more)

Map of Science

September 3, 2010 – 5:55 am

From time to time, maps representing the structure of modern science appear and try to widen our knowledge. You may remember when Wired published the “milky way” map of science or the map contrsucted by Nature using 800,000 scientific papers. Although, I think, these didn’t let us closer to get a global picture of what the map of modern science is like, but now, the Power of Data Visualization released a new one with a much clearer structure.

Click on the image to access the whole infographics.


MDLifeSucks: Share Your Story

September 2, 2010 – 4:03 pm

Of course, there is a reason why doctors become doctors (I have my own – to become a geneticist), but sometimes MD life is really not like what we expected. MDLifeSucks collects these negative stories and encourages you to share yours. A few examples:

I made the mistake of buying an MD license plate. Now, every time I go to the mechanic for a simple oil change, they find something new wrong with my car.

I put back a patient’s gown in the scrub dispenser machine and now my scrub machine privileges are revoked and the security camera picture of me doing so is plastered on the wall for all to see. MDLS.

I had to do a rectal exam on a 79 year old patient. She moaned. MDLS

Just realized I won’t make any real money until I’m 30. MDLS.

See more stories on the site