Cure me of deafness? no thanks
New scientific techniques may restore the hearing of millions of deaf people, but Jessica Fellowes doesn’t want it. (Source: Telegraph Health)
New scientific techniques may restore the hearing of millions of deaf people, but Jessica Fellowes doesn’t want it. (Source: Telegraph Health)
Prescribing magnesium sulfate to women at risk for preterm delivery reduces their risk of having a child with cerebral palsy, research confirms. (Source: MedWire News – Ob/Gyn)
Objective To compare the effectiveness and safety of three types of stents (sirolimus eluting, paclitaxel eluting, and bare metal) in people with and without diabetes mellitus.
Design Collaborative network meta-analysis.
Data sources Electronic databases (Medline, Embase, the Cochrane Central Register of Controlled Trials), relevant websites, reference lists, conference abstracts, reviews, book chapters, and proceedings of advisory panels for the US Food and Drug Administration. Manufacturers and trialists provided additional data.
Review methods Network meta-analysis with a mixed treatment comparison method to combine direct within trial comparisons between stents with indirect evidence from other trials while maintaining randomisation. Overall mortality was the primary safety end point, target lesion revascularisation the effectiveness end point.
Results 35 trials in 3852 people with diabetes and 10 947 people without diabetes contributed to the analyses. Inconsistency of the network was substantial for overall mortality in people with diabetes and seemed to be related to the duration of dual antiplatelet therapy (P value for interaction 0.02). Restricting the analysis to trials with a duration of dual antiplatelet therapy of six months or more, inconsistency was reduced considerably and hazard ratios for overall mortality were near one for all comparisons in people with diabetes: sirolimus eluting stents compared with bare metal stents 0.88 (95% credibility interval 0.55 to 1.30), paclitaxel eluting stents compared with bare metal stents 0.91 (0.60 to 1.38), and sirolimus eluting stents compared with paclitaxel eluting stents 0.95 (0.63 to 1.43). In people without diabetes, hazard ratios were unaffected by the restriction. Both drug eluting stents were associated with a decrease in revascularisation rates compared with bare metal stents in people both with and without diabetes.
Conclusion In trials that specified a duration of dual antiplatelet therapy of six months or more after stent implantation, drug eluting stents seemed safe and effective in people both with and without diabetes.
We’re very lucky: we’re homeschooling our son with autism. Truth is, we fought the system for five years, and then decided we’d all be better served (and much happier)…
We’re very lucky: we’re homeschooling our son with autism. Truth is, we fought the system for five years, and then decided we’d all be better served (and much happier)…
Abstract According to the microcosmic Syndrome Differentiation, immunological infertility is recognised as Kidney Yin Deficiency-Hyperactivity
of Fire Syndrome. Zhibai Dihuang Pills
, a recipe of Chinese medicinal herbs which plays a nourishing Yin to remove Fire action, was used to treat the infertile
couples with antisperm and/or antizona pellucida antibodies in their blood serum. It was found that after the treatment, the
antibodies were converted to negativeness in 81.3% of 32 immunological infertile couples. All 8 cases of successful pregnancy
occurred in 1?9 months after negative conversion of the antibodies and the negative status was maintained throughout the course
of pregnancy.
Content Type Journal ArticleCategory Original ArticlesDOI 10.1007/BF02940692Authors
Da-jin Li, Shanghai Medical University Dept. of Reproductive Immunology, Institute of Obstetrics and Gynecology 200011 ShanghaiChao-jing Li, Shanghai Medical University Dept. of Reproductive Immunology, Institute of Obstetrics and Gynecology 200011 ShanghaiYing Zhu, Shanghai Medical University Dept. of Reproductive Immunology, Institute of Obstetrics and Gynecology 200011 Shanghai
Journal Chinese Journal of Integrative MedicineOnline ISSN 1993-0402Print ISSN 1672-0415
Journal Volume Volume 1
Journal Issue Volume 1, Number 4 / December, 1995 (Source: Chinese Journal of Integrative Medicine)
Do you want to hear more about the impact of recent reforms on dentists, dental care professionals and patients? A conference exploring changes in regulation affecting dentistry will be taking place on 9 October 2008 at Woburn House in London.
A Berlin research team led by Professor Erich E. Wanker of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, has been awarded this year’s Erwin Schrodinger Prize for creating a unique “connection scheme” showing for the first time how thousands of human proteins – the building blocks and machines of life – interact with each other.
Premature infants whose mothers smoked during pregnancy may be at even higher risk for sudden infant death syndrome (SIDS) than preemies whose mothers did not smoke, according to new research out of the University of Calgary.