01 Apr 10 Kaposi’s sarcoma

Kaposi’s sarcoma (KS) is a rare type of cancer. It differs from other types of cancers in the way that it develops. (Source: New on NHS Direct)

 

MedWorm Sponsored Message: Find out how you can get your message across here by sponsoring this MedWorm news feed.

09 Mar 10 Hepatocellular carcinoma: Comparison of two different periods at the same center.

CONCLUSION: This study shows that over the last decade a number of characteristics of patients with HCC in our region have changed, particularly age at onset of HCC, staging of underlying liver disease and staging of HCC.
PMID: 20206885 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)

09 Mar 10 Guillain-Barre Syndrome as a Paraneoplastic Manifestation of Small-Cell Carcinoma of Lung

Could this patient’s Guillain-Barre syndrome (GBS) be a paraneoplastic response to small cell lung carcinoma? Southern Medical Journal (Source: Medscape Today Headlines)

08 Mar 10 Adenocarcinoma of Colon Presenting As Cushing’s Syndrome [DIAGNOSIS IN ONCOLOGY]

(Source: Journal of Clinical Oncology)

08 Mar 10 The expanding clinical profile of anti-ampa receptor encephalitis

(Source: Neurology)

08 Mar 10 Positron Emission Tomography-Computed Tomography in Paraneoplastic Neurologic Disorders: Systematic Analysis and Review [Original Contribution]

Conclusion  In a paraneoplastic neurologic context, PET-CT improves the detection of cancers when other screening test results are negative, particularly in the setting of seropositivity for a neuronal nuclear or cytoplasmic autoantibody marker of cancer.
Published online January 11, 2010 (doi:10.1001/archneurol.2009.336). (Source: Archives of Neurology)

08 Mar 10 Paraneoplastic Neurologic Syndrome in the PNS Euronetwork Database: A European Study From 20 Centers [Original Contribution]

Conclusion  The study results confirm that PNS influences oncologic patient survival. Tumors are the main cause of death, but some types of PNS (such as dysautonomia) have a poorer prognosis than malignant neoplasms. (Source: Archives of Neurology)

08 Mar 10 Targeting leukemia stem cells

Authors: Hanna K A Mikkola, Caius G Radu & Owen N Witte
Acute myeloid leukemia stem cells can be made susceptible to chemotherapy by inducing them to divide. (Source: Nature Biotechnology)

08 Mar 10 Growth hormone modulation of EGF signaling

The relevance of growth factors to the pathogenesis of human cancer has long been established. Among the growth factors and growth factor receptors that have been shown to be involved in the pathogenesis and progression of different carcinoma types is the epidermal growth factor (EGF) family of peptide growth factors and the EGF receptor. Growth hormone (GH) has been previously described to regulate hepatic EGFR expression.

Gonzales et al. analyzed EGF signaling pathways in two different in vivo models: one resistant to the actions of and the other with increased circulating GH levels (transgenic mice overexpressing bovine GH). Their study provides evidence not only for the crosstalk between GH and EGF signaling in the liver but also for different mechanisms controlling EGF-induced signa…

08 Mar 10 Working outdoors reduces cancer risk

Research shows vitamin D, produced by skin when exposed to ultraviolet light, associated with reduced rate of renal cancerMen who work outdoors, enabling their bodies to create vitamins through exposure to sunlight, have a reduced risk of kidney cancer, researchers said today.In the largest study of its kind, scientists found that vitamin D – produced by the skin when exposed to ultraviolet light – was associated with a reduced rate of renal cancer of up to 73% among men.However, the study, published by the American Cancer Society, found that the reduced risk only applied to men – there was no drop in renal cancer among the women studied who worked outdoors.The researchers, from the National Cancer Institute in the US, said the study of 2,500 workers in central Europe supported emerg…