06 Feb 10 Diagnostic accuracy of esophageal capsule endoscopy versus conventional upper digestive endoscopy for suspected esophageal squamous cell carcinoma

Endoscopy 2010; 42: 93-97DOI: 10.1055/s-0029-1243856 A video capsule similar to that used in small-bowel capsule endoscopy is now available for esophageal exploration. The aim of our study was to compare the accuracy of upper endoscopy (esophageal gastroduodenoscopy [EGE]) with esophageal capsule endoscopy (ECE) in patients at risk of esophageal squamous cell cancer (SCC).[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Endoscopy)

06 Feb 10 Benefits Of CyberKnife Radiosurgery For Lung Cancer Drive Continued Adoption

Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced that more than 12,000 courses of lung cancer treatment have been completed with CyberKnife radiosurgery. Usage of CyberKnife radiosurgery for lung cancer continues to grow, as illustrated by a 25 percent increase year over year in calendar year 2009... (Source: Lung Cancer News From Medical News Today)

06 Feb 10 New Agent To Manage Cancer Related Effusions

In the USA each year, 200,000 cancer patients suffer from a malignant pleural effusion development of excessive fluid (pleural effusion) in the chest. Several litres of such fluid can accumulate, and many patients suffer from significant breathlessness and distress. One in four patients with lung cancer, one in every three with breast cancer and most of the patients with mesothelioma will develop a malignant effusion. The current strategy is to induce a pleurodesis (seal the pleural cavity with a chemical agent so no fluid can accumulate)... (Source: Health News from Medical News Today)

06 Feb 10 Benefits Of CyberKnife Radiosurgery For Lung Cancer Drive Continued Adoption

Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced that more than 12,000 courses of lung cancer treatment have been completed with CyberKnife radiosurgery. Usage of CyberKnife radiosurgery for lung cancer continues to grow, as illustrated by a 25 percent increase year over year in calendar year 2009. CyberKnife radiosurgery offers lung cancer patients a non-invasive means for treating their disease. The outpatient treatment is completed in five or fewer visits, and is both painless and non-surgical... (Source: Health News from Medical News Today)

06 Feb 10 Does screening history explain the ethnic differences in stage at diagnosis of cervical cancer in New Zealand?

Conclusions Over half of cases had not been ‘ever screened’. Regular screening substantially lowered the risk of being diagnosed at a late stage. However, screening history does not appear to explain the ethnic differences in stage at diagnosis. (Source: International Journal of Epidemiology)

06 Feb 10 The treatment of solid tumors by alpha emitters released from (224)Ra-loaded sources-internal dosimetry analysis.

Authors: Arazi L, Cooks T, Schmidt M, Keisari Y, Kelson I Diffusing alpha-emitters radiation therapy (DART) is a proposed new form of brachytherapy, allowing the treatment of solid tumors by alpha particles. DART utilizes implantable sources carrying small activities of radium-224, which continually release into the tumor radon-220, polonium-216 and lead-212 atoms, while radium-224 itself remains fixed to the source. The released atoms disperse inside the tumor by diffusive and convective processes, creating, through their alpha emissions, a high-dose region measuring several mm in diameter about each source. The efficacy of DART has been demonstrated in preclinical studies on mice-borne squamous cell carcinoma and lung tumors and the method is now being developed toward clinical trial...

05 Feb 10 FDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma

Conclusions: FDG-PET/CT has a potential relevant impact in staging and target volume delineation of the carcinoma of the anal canal. Clinical stage variation occurred in 18.5% of cases with change of treatment intent in 3.7%. The GTV and the CTV changed in shape and in size based on PET/CT imaging. (Source: Radiation Oncology)

05 Feb 10 Men who eat soy may have lower lung cancer risk

NEW YORK (Reuters Health) - Men who don't smoke and eat a lot of soy may have a lower risk of lung cancer, according to a new study. (Source: Reuters: Health)

05 Feb 10 Pharmacokinetic study of gemcitabine, given as prolonged infusion at fixed dose rate, in combination with cisplatin in patients with advanced non-small-cell lung cancer

Conclusions  A substantially higher accumulation of metabolites in peripheral blood mononuclear cells was observed when the longer infusion time was employed, suggesting a pharmacological advantage for this treatment schedule. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00280-010-1255-7Authors Orazio Caffo, Santa Chiara Hospital Medical Oncology Department Trento ItalyStefania Fallani, University of Florence Department of Pharmacology Florence ItalyElena Marangon, Istituto di Ricerche Farmacologiche “Mario Negri” Laboratory of Cancer Pharmacology, Department of Oncology Milan ItalyStefania Nobili, University of Florence Department of Pharmacology Florence ItalyMaria Iris Cassetta, University of Florence Department of Pharmacology Florence It...

05 Feb 10 Risk stratification of solitary pulmonary nodules by means of PET using 18F-fluorodeoxyglucose and SUV quantification

Conclusion  FDG PET allows assessment of the individual risk for malignancy in SPNs by considering tumoural SUV and pre-test probability. Higher FDG uptake in lung cancer as measured by SUV analysis is a prognostic factor. In patients with low FDG uptake in an SPN and increased risk during surgery omission of diagnostic thoracotomy may be warranted. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-010-1387-3Authors Aleksandar Grgic, Saarland University Medical Center Department of Nuclear Medicine Gebäude 50 66421 Homburg/Saar GermanyYildirim Yüksel, Saarland University Medical Center Department of Nuclear Medicine Gebäude 50 66421 Homburg/Saar GermanyAndreas Gröschel, Saarland University Medical Center Department of Internal Medicine V (Pneu...