Archive for October, 2009

Rheumatoid arthritis-associated interstitial lung disease: the relevance of histopathologic and radiographic pattern.

Saturday, October 31st, 2009

Authors: Kim EJ, Collard HR, King TE Interstitial lung disease (ILD) is a frequent extraarticular manifestation of rheumatoid arthritis (RA). While the nonspecific interstitial pneumonia pattern predominates in most forms of connective tissue-associated ILD, studies in patients with RA-associated ILD (RA-ILD) suggest that the usual interstitial pneumonia ...

Axonal Common Peroneal Nerve Palsy and Delayed Proximal Motor Radial Conduction Block Following Infliximab Treatment

Saturday, October 31st, 2009

A 38-year-old female, treated with infliximab (3mg/kg) for a two-year history of psoriatic arthritis, was referred with a sudden onset of left foot drop. At referral, eight courses of infliximab (anti-tumor necrosis factor [anti-TNF] monoclonal antibody) had already been infused. Her past medical history was otherwise unremarkable. No familial history ...

Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritis

Saturday, October 31st, 2009

Conclusion: Our data indicate that Y145 is the most critical tyrosine supporting SLP-76 function in myeloid cells. Future efforts to dissect how Y145 mediates SLP-76–dependent signaling in MCs and PMNs will increase our understanding of these lineages and provide insights into the treatment of allergy and inflammation. (Source: Journal of ...

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

Saturday, October 31st, 2009

Conclusion: Although both responders and nonresponders to etanercept inactivated sepsis cascade cytokines, response to etanercept is dependent on inactivation of myeloid dendritic cell genes and inactivation of the TH17 immune response. (Source: Journal of Allergy and Clinical Immunology)

Opening-wedge high tibial osteotomy with a locked low-profile plate.

Saturday, October 31st, 2009

CONCLUSIONS: Our results suggest that an opening-wedge high tibial osteotomy with locked plate fixation allows a correct valgus angle to be achieved with good short-term results. PMID: 19884431 [PubMed - in process] (Source: The Journal of Bone and Joint Surgery. American volume)MedWorm Message: Get the very latest ...

Comparison of arthroscopic and open treatment of septic arthritis of the wrist.

Saturday, October 31st, 2009

Authors: Strauch RJ PMID: 19884463 [PubMed - in process] (Source: The Journal of Bone and Joint Surgery. American volume)

Outcomes of Silicone Arthroplasty for Rheumatoid Metacarpophalangeal Joints Stratified by Fingers

Saturday, October 31st, 2009

Conclusions: Our hypothesis that the ulnar fingers would have worse outcomes than the radial fingers was not proven by this study. Although experiences have indicated that it is more difficult to maintain posture for the ring and little fingers after SMPA owing to the deforming forces, sufficient correction of the ...

MR Imaging in Congenital and Acquired Disorders of the Pediatric Upper Extremity

Saturday, October 31st, 2009

This article rounds out the issue on pediatric musculoskeletal MR imaging. It focuses on the evaluation of more common congenital disorders, and mainly sports-related injuries of the shoulder, elbow, and wrist in children. MR imaging can be more challenging in diagnosis of some of these disorders. Features of overuse injuries ...

MR Imaging of Pediatric Arthritis

Saturday, October 31st, 2009

This article discusses MR imaging findings of juvenile idiopathic arthritis, enthesis-related arthritis, juvenile psoriatic arthritis, and articular findings in collagen vascular diseases, septic arthritic, hemophilia, neuroarthropathy, and pseudoarthridities. (Source: Radiologic Clinics of North America)

Infectious and Inflammatory Disorders

Saturday, October 31st, 2009

Osteomyelitis and inflammatory arthritis affect many children. In this article, the authors describe clinical, pathophysiologic, and imaging characteristics of common (and a few not-so-common) conditions in these categories. Emphasis is placed on MR imaging characteristics, but the article discusses other imaging modalities and clinical evaluation when appropriate. Having a thorough ...